DGNM Annual Meeting 2023

The Annual Meeting 2023 of the German Society for Neurogastroenterology and Motility e.V. will take place from 03 - 05 March 2023 in Berlin on the premises of the Evangelischen Diakonievereins Berlin-Zehlendorf e.V.

Programme

3. - 5. März 2023

FRIDAY, 3. März 2023

until 18:00 Arrival and dinner
from 19.30 Social evening in the conference café

SATURDAY, 4 March 2023

8.00 Openin (A Stengel/Tübingen-Berlin, R Patejdl/Rostock)

Session I:
Basic - Translational - Models, Diagnostics, Treatment
(Vorsitz: R Patejdl, Rostock)

8.00 – 8.15 Recordings from gastric mechanosensitive neurons (S Mayr, R Schliep, G Mazzuoli-Weber, Hannover)
8.15 – 8.30 Anti-inflammatory mechanisms of action in herbs – a key to their action in FGID (O Kelber, K Nieber, M T Khayyal, Darmstadt, Kairo - EGY)
8.30 – 8.45 The herbal preparation, STW 5-II, is effective against experimental colitis due to its anti-inflammatory and antioxidant properties (M T Khayyal, W Wadie, O Kelber, H Aziz-Kalbhenn, Kairo - EGY, Darmstadt)
8.45 – 9.00 Food intake microstructure in a chronic activity-based anorexia rat model (V Hanel, M A Schalla, T Friedrich, M Goebel-Stengel, P Kobelt, M Rose, A Stengel, Berlin, Rottweil, Tübingen)
9.00 – 9.15 FNerve-derived CXCL8 promotes perineural invasion and associates with poor survival in pancreatic cancer (C Mota Reyes, K Cifcibasi, T Zwick, G Liptay, A Muckenhuber, K Steiger, W Weichert, H Algül, H Friess, R Istvanffy, I E Demir, München)
9.15 – 9.30 The potential usefulness of Itopride in irritable bowel syndrome involves serotonergic and stress-related pathways along the brain-gut axis (M T Khayyal, R M Abdelsalam, L N Gadelrub, Hannover, Kairo - EGY)
9.30 – 9.45 Functional neuroimaging from myenteric neurons of the human colon (A S Sehnert*, K Elfers, G Mazzuoli-Weber, Hannover)
9.45 – 10.15 Coffee break

Prize Lectures Research Prize Neurogastroenterologie
(Vorsitz: T Frieling, Krefeld)

10.15 – 10.45 Gut feelings that teach the brain to fear pain - Context-dependent activation of the central fear network in an interoceptive conditioning paradigm (A Icenhour, L Petrakova, N Hazzan, N Theysohn, C J Merz, S Elsenbruch, Bochum, Essen)
10.45 – 11.15 Intestinal epithelial stem cell modulation by neuronal messengers (M Middelhoff, München)

Lunchsymposium Mikrobiom
(Vorsitz: A Stengel, Tübingen/Berlin)

11.15 – 11.45 Gut microbiome - what do we know so far? (D Guseva, Karlsruhe)
11.45 – 12.15 Probiotics – where can we use them? (M Goebel-Stengel, Rottweil/Tübingen)
12.15 – 13.15 Lunch break

Session II:
Basic - Inflammation and Stress
(Vorsitz: M Sachez-Ruis, Köln)

13.15 – 13.30 Localization pattern of Dispatched Homolog 2 (DISP2) in the central and enteric nervous system (F Cossais, M Heimke, M Böttner, F Richter, T Wedel, J-H Egberts, R Lucius, Kiel, Hamburg)
13.30 – 13.45 ?-Adrenergic signaling evokes an enteric glia inflammatory reaction, acute enteric gliosis and neuroimmunological changes after surgery (P Leven, R Schneider, L Schneider, S Mallesh, J C Kalff, S Wehner, Bonn)
13.45 – 14.00 Deletion of neuronal IL-6-signaling leads to increased postoperative inflammation and delayed recovery of intestinal homeostasis (R Schneider, P Leven, K D Siemens, M Brefler, J C Kalff, S Wehner, Bonn)
14.00 – 14.15 Niacin beneficially affects gut inflammation and depressive behavioural disorders in DSS-induced colitis through acting on GPR109A receptor (M T Khayyal, W Wadie, S S Mohamed, E A Abd El-Haleim, Kairo - EGY)
14.15 – 14.30 LCMV infection can activate low-affinity OVA-specific CD8 T cells to induce autoimmunity against enteric neurons in experimental autoimmune enteric ganglionitis (M Sachez-Ruis*, O Utermöhlen, A Brunn, M Deckert, Köln)
14.30 – 14.15 TRPV3 and TRPV4: additional pathways for the uptake of Ca2+ by the intestine? (F Stumpff, D Manneck, Potsdam)

Session III:
Basic - Motility
(Vorsitz: P Neckel, Tübingen)

14.45 – 15.00 Effects of methylen blue and global photo lesioning on the long-distance-contractions of the murine colon (R Patejdl, N Brinckmann, Rostock)
15.00 – 15.15 The spasmolytic effects of fennel tea on gastric smooth muscle of guinea pig are independent of nitric oxide production, and are mediated by calcium channels (N Mansouri, B Kuch, H Luksch, M Schemann, A Annaházi, Freising, München)
15.15 – 15.30 Human neuropsin (hOPN5) as a new tool to control gastric contractility (D Zipf, M Vogt, R Patejdl, T Brügmann, Göttingen, Rostock)
15.30 – 15.45 Parallel optogenetic and electric field stimulation of gastric fundus muscle - who‘s in the lead? (L Grabe, T Brügmann, R Patejdl, Rostock, Göttingen)
15.45 – 16.00 Gap junction-dependent and -independent cell coupling in smooth muscle of the murine gastric antrum (L Schörner*, T Brügmann, R Patejdl, Rostock, Göttingen)
16.00 – 16.15 Characterizing methylene blue phototoxicity in isolated gastrointestinal tissue: function and morphology (D Lehrke, F Cossais, N Brinckmann, B Schulz, R Patejdl, Rostock)
16.15 – 16.45 Coffee break

Session IV:
Basic - ENS
(Vorsitz: G Mazzuoli-Weber, Hannover)

16.45 – 17.00 Transcriptional profiling of the enteric nervous system during intestinal inflammation (C Klose, Berlin)
17.00 – 17.15 Enteric neuroanatomy and smooth muscle activity in the western diamondback (L Ridzal, T Kohl, B Kuch, M Hartel, K Michel, H Luksch, M Schemann, A Annaházi, Freising)
17.15 – 17.30 The effect of heparan sulfate proteoglycans on homeostasis in the ENS (J N van den Beld, M Scharr, S Scherer, P H Neckel, Tübingen)
17.30 – 17.45 A novel crosstalk between intestinal opioid-producing regulatory T cells and enteric neurons in the control of gastrointestinal (GI) functions (C Cosovanu, G Mazzuoli-Weber, C Neumann, Berlin, Hannover)
17.45 – 18.00 LGR/R-Spondin1 signaling drives postnatal enteric neuronal differentiation in mice and human (M Scharr*, S Scherer, P H Neckel, Tübingen)
18.00 – 18.15 Mechanosensitivity of enteric neurones in the gastric fundus and antrum (S Mayr*, R Schliep, G Mazzuoli-Weber, Hannover)
18.15 – 19.00 Dinner
19.00 – 21.00 Mitgliederversammlung
ab 21.00 Geselliger Abend im La Fontaine

Sunday, 5 March 2023

Session V:
Clinical - Pathophysiology, Diagnostics and Treatment
(M Goebel-Stengel, Rottweil/Tübingen)

9.00 – 9.15 Scientific concept of the SOMACROSS Research Unit (RU 5211): Persistent somatic symptoms in gastroenterology and beyond (K Maehder, V Andresen, O Van den Bergh, T B. Huber, O von dem Knesebeck, A W. Lohse, Y Nestoriuc, G Schneider, S W Schneider, C Schramm, S Ständer, E Vettorazzi, A Zapf, M Shedden-Mora, A Toussaint, B Löwe, Hamburg, Leuven, Münster)
9.15 – 9.30 Persistence of gastrointestinal symptoms in irritable bowel syndrome and ulcerative colitis - study protocol of the SOMACROSS Research Unit SOMA.GUT -RCT (L Peters, K Maehder, S Hübener, Y Nestoriuc, V Andresen, E Vettorazzi, A Zapf, A W Lohse, B Löwe, Hamburg)
9.30 – 9.45 Association between pancreatic exocrine function, carbohydrate malabsorption and gastrointestinal transit in healthy volunteers (J Keller, V Andresen, Hamburg)
9.45 – 10.00 REACH foundation - Research, Education & Awareness for Children with Hirschsprung disease (E Schnadig, Concord, USA)

Lüderitz Lecture
(A Stengel, Tübingen/Berlin)

10.00 – 10.45 Care for patients with irritable bowel syndrome - an integrative approach (V Andresen, Hamburg)
10.00 – 10.15 Coffee break

Session VI:
Clinical - Endoscopy
(Vorsitz: J Keller, Hamburg)

11.15 – 11.30 Endoscopic laser endomicroscopy and leaky gut in patients with functional gastrointestinal symptoms and food intolerance (T Frieling, B Gjin, I Melchior, P Euler, C Kreyse, S Kalde, B Krummen, R Kiesslich, B Hemmerlein, Krefeld, Wiesbaden)
11.30 – 11.45 Gastrointestinal adverse reaction to food (GARF) in patients with functional abdominal pain: Evaluation through endoscopic confocal laser endomicroscopy (T Frieling, B Gjini, I Melchior, P Euler, C Kreyse, S Kalde, B Krummen, R Kiesslich, B Hemmerlein (Krefeld, Wiesbaden)
11.45 – 12.00 Endoscopic tunneling procedures in motility disorders oft the gastrointestinal tract (F Gundling, Bamberg)
12.00 Farewell (A Stengel/Tübingen-Berlin, R Patejdl/Rostock)
12.00 Lunch (Lunch Boxes) and return home

A * after the name indicates that there is an application for a Wienbeck Travel Scholarship.

Registration

03 - 05 March 2023

Here you will find the possibility to register bindingly for the DGNM Annual Meeting 2023.